Primeadine® Original Spermidine Supplement - Oxford Healthspan

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1 bottle / 30 day supply
Buy 3 bottles and get 5% discount

Promote healthy aging with Primeadine® Original plant-derived spermidine supplements. Each serving provides 1mg of spermidine in its purest, most bioavailable form from concentrated and defatted wheat germ extract.

The wholly food-derived spermidine in Primeadine® Original also comes with naturally co-occurring polyamines, putrescine and spermine. These additional polyamines, plus the special prebiotic fiber we add to support spermidine production in your gut biome, are part of a virtuous recycling loop that helps your body make more spermidine.

What are the benefits?

  • Supports sleep quality
  • Promotes hair growth
  • Supports skin and nail health
  • Promotes energy and vitality
  • Supports memory, cognition, and brain health
  • Helps maintain gut health
  • Promotes hormonal balance
  • Mimics the benefits of fasting

 Check out the video below which also has testimonials and information. 
You can also click here to see reviews from Trustpilot.
Nadine Artemis, founder of Living Libations, talks with Leslie Kenny (founder of Primeadine) in the podcast below. 


Key Ingredients:

Primeadine® Original is wholly plant-derived and contains 1mg of supplemental spermidine. It also includes the beneficial and naturally co-occurring polyamines, spermine and putrescine, and an added prebiotic fiber, FOS (Fructooligosaccharide) - both of which help your body produce more spermidine.

Concentrated Japanese Wheat Germ Extract
Spermidine and other beneficial polyamines, spermine and putrescine, are abundant in wheat germ. However, the quality of wheat germ can vary significantly. We obtain a potent wheat germ extract from Japan, a region known for its longevity and strict food safety protocols. To maintain its quality and prevent rancidity, we go one step further and remove its omega-6 fatty acid content. Rancid omega-6 fatty acids can become part of our cells and cause inflammation in the body.

FOS (Fructooligosaccharide)
The unique prebiotic fiber, FOS (fructooligosaccharide), in Primeadine® Original nourishes the gut microbiome's spermidine-producing bacteria, enhancing the body's innate ability to produce its own spermidine. FOS is found in a resistant starch, called maltodextrin, which we source from beetroot.

  • Each serving provides 1mg of supplemental plant-derived spermidine from concentrated, defatted Japanese wheat* germ extract. We defat our wheat germ extract to remove the omega 6 fatty acids (PUFAs). We do this as these can easily go rancid and become part of the outer cell membrane where they cause inflammation and leak cell components. Defatted wheat germ is also more easily absorbed in the GI tract due to its high molecular mass.

Other ingredients:
Hypromellose (plant cellulose capsule).
Sodium citrate.


How to Use:

Serving size: 3 capsules per day, taken with liquid at mealtime.

For long term use:

We suggest taking Primeadine® with your last meal to kickstart autophagy before bed, or with your breakfast to extend the benefits of your overnight fast.

For first time use:

However, the first time you take it we recommend working up to the full daily dosage over 3 consecutive days.

Day 1: Take 1 capsule with liquid at mealtime.

Day 2: Take 2 capsules with liquid at mealtime.

Day 3: Take 3 capsules with liquid at mealtime and if well tolerated, continue at this dose.


If you find 3 capsules too many to take at once, you can split the dose across the day, or open the pills and add the contents to food or drink (below 40 degrees celsius/104 degrees fahrenheit).

Primeadine® Original is a wholly plant-derived spermidine supplement for aging well and triggering cell renewal (autophagy).

Each serving provides 1mg of the purest, most bioavailable spermidine from concentrated and defatted Japanese wheat germ extract. As well as increasing your spermidine levels, Primeadine® Original reactivates your natural ability to make spermidine in your gut biome thanks to the inclusion of a special prebiotic fiber.

  • Supports sleep quality and circadian rhythm
  • Enhances hair growth
  • Supports skin and nail health
  • Promotes energy and vitality
  • Helps maintain gut health

Made from concentrated & defatted Japanese wheat germ extract
Supports natural spermidine production with added prebiotic fiber
Each serving contains 1mg of supplemental spermidine
No synthetics, fillers, GMOs, pesticides, heavy metals, or PUFAs
ISO22000 standard, the highest in food quality control
Vegan & cruelty free


  • Synthetics
  • GMOs
  • Soy
  • Lactose
  • PUFAs (polyunsaturated fatty acids)
  • Heavy Metals
  • Toxins
  • Fillers
  • Flow agents
  • Sugar
  • Gelatin

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